What is Injection Therapy?
Injection therapy delivers medication directly to the site of pain or inflammation, providing targeted relief when oral medications or other conservative treatments haven't been effective. At our Belfast clinics we offer a comprehensive range of injection therapies for the knee, foot, and ankle, performed privately with no GP referral needed.
All injections are performed using real-time ultrasound guidance, ensuring the medication reaches exactly the right location for maximum effectiveness and safety. This precision approach significantly improves outcomes compared to landmark-guided (blind) injections.
We offer three specialist injection types, each designed to target different conditions and stages of pathology:
Common Symptoms
- Persistent joint pain and stiffness
- Swelling and chronic inflammation
- Pain that limits daily activities or sport
- Mid-portion Achilles tendon thickening and pain
- Early to moderate osteoarthritis symptoms
- Burning or tingling sensations (neuromas)
- Pain not responding to other conservative treatments
- Joint stiffness and reduced range of motion
Common Causes
- Morton's neuroma
- Plantar fasciitis
- Knee, ankle & foot osteoarthritis
- Mid-portion Achilles tendinopathy
- Bursitis (knee, heel, ankle, or forefoot)
- Capsulitis (joint inflammation)
- Insertional tendinopathy
- Synovitis and joint effusion
Our Treatment Approach
We offer three distinct types of injection therapy, each selected based on your specific diagnosis, the stage of your condition, and your treatment goals:
Corticosteroid (Cortisone) Injections
Corticosteroid injections are a powerful anti-inflammatory treatment used to rapidly reduce swelling, pain, and inflammation in joints, bursae, and soft tissues. They are one of the most widely used and evidence-based injection treatments in musculoskeletal medicine.
Commonly used for: plantar fasciitis, Morton's neuroma, bursitis (heel, ankle, forefoot), capsulitis, synovitis, and acute inflammatory joint conditions.
How it works: A corticosteroid (such as methylprednisolone or triamcinolone) is injected directly into the affected area under ultrasound guidance. The steroid suppresses the local inflammatory response, providing significant pain relief. This is often combined with a local anaesthetic for immediate comfort during the procedure.
What to expect: Relief typically begins within 3–7 days and can last from 6 weeks to several months. We generally limit corticosteroid injections to 2–3 per year in any one area to protect tissue integrity.
Hyaluronic Acid Injections (Viscosupplementation)
Hyaluronic acid (HA) injections provide natural replenishment of joint lubrication for patients with early to moderate osteoarthritis. Hyaluronic acid is a naturally occurring substance found in healthy synovial (joint) fluid. It acts as both a lubricant and a shock absorber within the joint.
Commonly used for: early to moderate osteoarthritis of the ankle, midfoot, and first metatarsophalangeal (big toe) joint. Particularly suitable for patients who want to avoid or delay surgical intervention, or those who cannot tolerate repeated corticosteroid use.
How it works: The injection supplements the joint's depleted natural hyaluronic acid, restoring the viscosity and elasticity of the synovial fluid. This reduces friction between cartilage surfaces, decreases pain, and improves joint mobility. Unlike corticosteroids, HA injections work by restoring the joint's natural environment rather than simply suppressing inflammation.
What to expect: Benefits may take 2–4 weeks to develop fully and can last 6–12 months. A course of 1–3 injections may be recommended depending on the joint and severity. HA injections are well-tolerated with minimal side effects and can be repeated as needed.
High Volume Injections (HVI) for Mid-Portion Achilles Tendinopathy
High volume injection (HVI) therapy is a specialist treatment for chronic mid-portion Achilles tendinopathy, a condition characterised by tendon thickening, pain, and stiffness in the middle section of the Achilles tendon, typically 2–6cm above the heel bone.
How it works: Under real-time ultrasound guidance, a large volume of injectable fluid (typically a combination of normal saline, local anaesthetic, and a small amount of corticosteroid) is injected into the space between the Achilles tendon and the surrounding paratenon (Kager's fat pad). The high volume of fluid mechanically disrupts and strips away the abnormal neovascularisation (new blood vessel and nerve ingrowth) that develops in chronic tendinopathy. These abnormal vessels are strongly associated with pain.
The evidence: Research has shown that HVI can significantly reduce pain scores and improve function in patients with chronic mid-portion Achilles tendinopathy, particularly when combined with a structured eccentric loading rehabilitation programme. It is considered when conservative management (physiotherapy, shockwave therapy, load management) has plateaued.
What to expect: The procedure takes approximately 10–15 minutes. You may feel pressure as the volume is injected. Some patients notice immediate improvement, while others respond over the following 2–4 weeks. A structured rehabilitation programme is essential following the procedure to optimise outcomes.
What to Expect
Clinical Assessment
Treatment Selection
Informed Consent
Ultrasound-Guided Injection
Post-Injection Care
Follow-Up Review
Ready to book your injection therapy appointment?
"Have been attending the Lower Limb Clinic for a number of weeks and can not recommend them high enough. Darren is professional, so thorough, and explains everything fully. Diagnosis is accurate with the help of the scanner, which gives you comfort that the treatment is the best course of action. Just wish I had gone here much sooner!"
Denise Brown
Treated for: Diagnosis & Treatment · Google review
Frequently Asked Questions
Common questions about Injection Therapy at Lower Limb Clinic.

Clinically reviewed by Paul McMullan, BSc(Hons) MSc FRCPSGlasg MRCPod
BSc (Hons) Podiatry · MSc Podiatric Sports Medicine (QMUL) · FRCPSGlasg · MRCPod
Lead Podiatrist & Clinical Director, Lower Limb Clinic Belfast




